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Laboratory Research

The Neurosurgical Research Laboratories include four NIH-funded teams working in the areas of stroke, brain tumors, traumatic brain and spinal injury, encephalopathy, nanomedicine and advanced drug delivery, and tissue engineering.   Current funding exceeds $3 million per year, from numerous grants from the NIH, Department of Defense, Veterans Administration and private foundations. Twelve full-time research associates, assistants or specialists comprise the support for the wide-ranging translational research efforts of the laboratory. At any time, the lab employs a combination of post-docs, neurosurgical residents, medical students and graduate students who have historically been able to make unique contributions that have lead to numerous high-impact publications. This large mix of talented people provides a unique environment in which neurosurgical residents can develop their scientific interests. In past years, neurosurgery residents have been extremely successful in securing NREF funding, T32, and other grants.

The Neurosurgical Research Laboratories occupy over 6000 square feet in the School of Medicine. This space includes 5000 square feet of laboratory space plus 1100 square feet of adjoining office spaces and conference rooms. The laboratory space is divided into 4 separate wet labs, 4 cell culture rooms and 2 cold rooms for molecular and cellular work, 4 rooms that are used for animal surgeries and behavioral testing, and 1 room for patch clamp electrophysiology. The laboratories are internally connected to the primary site, the University Hospital and the academic offices. The laboratories are fully equipped and house state-of-the-art equipment.

Each year, residents are encouraged to participate in the work of the Neurosurgical research laboratories, and many do. For residents interested in areas of scientific investigation not directly addressed by laboratory faculty, there are also numerous additional opportunities on campus in the Neurosciences, as well as at neighboring institutions including the National Institutes of Health and Johns Hopkins University.

Research Support

Surgical Research Support

  • systems for the inhalation or injection of anesthesia
  • Stoelting stereotactic apparatuses
  • telemetry systems for blood pressure
  • flame photometer for tissue ion concentrations
  • immunoflorescence imaging
  • patch clamping equipment

Behavioral Research Support

  • Morris water maze
  • 5-choice serial reaction time task
  • RotaRod
  • Open field maze

Multimedia Research Support

  • computers
  • scanner
  • slide maker
  • printer
  • photography